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dsg 2  (MedChemExpress)


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    Structured Review

    MedChemExpress dsg 2
    Dsg 2, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 92/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/dsg+2/DSG2%2FDesmoglein-2%2C+Human/pmc11686370-367-13-14
    Average 92 stars, based on 2 article reviews
    dsg 2 - by Bioz Stars, 2026-09
    92/100 stars

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    Related Articles

    Binding Assay:

    Article Title: ALCAM is an entry factor for severe community acquired Pneumonia-associated Human adenovirus species B
    Article Snippet: The purified knob protein was validated by Orbitrap Fusion MS (Thermo Fisher, San Jose, CA) using Proteome Discoverer 2.2 and X calibur analysis software at the Analytical Chemistry Platform at SIAIS, ShanghaiTech University. .. To determine the binding affinity of knob with ALCAM (Sino, Cat. No. 10045-H08H-100), DSG-2 (MCE, Cat. No. HY-P77917) or knob, the SPR assay was carried out. .. We performed SPR experiments with a Biacore 8 K (Cytiva) instrument.

    SPR Assay:

    Article Title: ALCAM is an entry factor for severe community acquired Pneumonia-associated Human adenovirus species B
    Article Snippet: The purified knob protein was validated by Orbitrap Fusion MS (Thermo Fisher, San Jose, CA) using Proteome Discoverer 2.2 and X calibur analysis software at the Analytical Chemistry Platform at SIAIS, ShanghaiTech University. .. To determine the binding affinity of knob with ALCAM (Sino, Cat. No. 10045-H08H-100), DSG-2 (MCE, Cat. No. HY-P77917) or knob, the SPR assay was carried out. .. We performed SPR experiments with a Biacore 8 K (Cytiva) instrument.



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    Immunohistochemical detection of <t>DSG</t> in the meibomian glands of C57BL/6 mice. ( A ) DSG (red reaction product) is expressed throughout the acinus (ac). In the peripheral areas of the acinus, where basal cells (b) and differentiating meibocytes (d) are located, the immunoreaction seems to be stronger than in the central areas where mature (m) and hypermature (hm) meibocytes are located. The cell borders between individual meibocytes also seem to be more intensely stained, indicating the membrane-bound localization of DSG. ( B ) Transition of the disintegration zone (d) of an acinus (ac) into the connecting duct (cd). Parts of the duct are filled with degenerated cells and meibum and show a weak DSG reaction. The epithelium of the connecting duct is also positive for DSG, especially apically toward the lumen. Conjunctiva (cj). ( C ) Positive control is the detection of DSG in the epidermis (epi) of the eyelid. ( D ) The negative control shows no immunoreaction. The figure shows representative results of three independent experiments ( n = 3). DSG, desmoglein.
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    Immunohistochemical detection of <t>DSG</t> in the meibomian glands of C57BL/6 mice. ( A ) DSG (red reaction product) is expressed throughout the acinus (ac). In the peripheral areas of the acinus, where basal cells (b) and differentiating meibocytes (d) are located, the immunoreaction seems to be stronger than in the central areas where mature (m) and hypermature (hm) meibocytes are located. The cell borders between individual meibocytes also seem to be more intensely stained, indicating the membrane-bound localization of DSG. ( B ) Transition of the disintegration zone (d) of an acinus (ac) into the connecting duct (cd). Parts of the duct are filled with degenerated cells and meibum and show a weak DSG reaction. The epithelium of the connecting duct is also positive for DSG, especially apically toward the lumen. Conjunctiva (cj). ( C ) Positive control is the detection of DSG in the epidermis (epi) of the eyelid. ( D ) The negative control shows no immunoreaction. The figure shows representative results of three independent experiments ( n = 3). DSG, desmoglein.
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    Immunohistochemical detection of <t>DSG</t> in the meibomian glands of C57BL/6 mice. ( A ) DSG (red reaction product) is expressed throughout the acinus (ac). In the peripheral areas of the acinus, where basal cells (b) and differentiating meibocytes (d) are located, the immunoreaction seems to be stronger than in the central areas where mature (m) and hypermature (hm) meibocytes are located. The cell borders between individual meibocytes also seem to be more intensely stained, indicating the membrane-bound localization of DSG. ( B ) Transition of the disintegration zone (d) of an acinus (ac) into the connecting duct (cd). Parts of the duct are filled with degenerated cells and meibum and show a weak DSG reaction. The epithelium of the connecting duct is also positive for DSG, especially apically toward the lumen. Conjunctiva (cj). ( C ) Positive control is the detection of DSG in the epidermis (epi) of the eyelid. ( D ) The negative control shows no immunoreaction. The figure shows representative results of three independent experiments ( n = 3). DSG, desmoglein.
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    Immunohistochemical detection of <t>DSG</t> in the meibomian glands of C57BL/6 mice. ( A ) DSG (red reaction product) is expressed throughout the acinus (ac). In the peripheral areas of the acinus, where basal cells (b) and differentiating meibocytes (d) are located, the immunoreaction seems to be stronger than in the central areas where mature (m) and hypermature (hm) meibocytes are located. The cell borders between individual meibocytes also seem to be more intensely stained, indicating the membrane-bound localization of DSG. ( B ) Transition of the disintegration zone (d) of an acinus (ac) into the connecting duct (cd). Parts of the duct are filled with degenerated cells and meibum and show a weak DSG reaction. The epithelium of the connecting duct is also positive for DSG, especially apically toward the lumen. Conjunctiva (cj). ( C ) Positive control is the detection of DSG in the epidermis (epi) of the eyelid. ( D ) The negative control shows no immunoreaction. The figure shows representative results of three independent experiments ( n = 3). DSG, desmoglein.
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    Image Search Results


    Immunohistochemical detection of DSG in the meibomian glands of C57BL/6 mice. ( A ) DSG (red reaction product) is expressed throughout the acinus (ac). In the peripheral areas of the acinus, where basal cells (b) and differentiating meibocytes (d) are located, the immunoreaction seems to be stronger than in the central areas where mature (m) and hypermature (hm) meibocytes are located. The cell borders between individual meibocytes also seem to be more intensely stained, indicating the membrane-bound localization of DSG. ( B ) Transition of the disintegration zone (d) of an acinus (ac) into the connecting duct (cd). Parts of the duct are filled with degenerated cells and meibum and show a weak DSG reaction. The epithelium of the connecting duct is also positive for DSG, especially apically toward the lumen. Conjunctiva (cj). ( C ) Positive control is the detection of DSG in the epidermis (epi) of the eyelid. ( D ) The negative control shows no immunoreaction. The figure shows representative results of three independent experiments ( n = 3). DSG, desmoglein.

    Journal: Investigative Ophthalmology & Visual Science

    Article Title: Calcium-Dependent Regulation of Desmosomal Proteins in Human Meibomian Gland Epithelial Cells

    doi: 10.1167/iovs.66.6.49

    Figure Lengend Snippet: Immunohistochemical detection of DSG in the meibomian glands of C57BL/6 mice. ( A ) DSG (red reaction product) is expressed throughout the acinus (ac). In the peripheral areas of the acinus, where basal cells (b) and differentiating meibocytes (d) are located, the immunoreaction seems to be stronger than in the central areas where mature (m) and hypermature (hm) meibocytes are located. The cell borders between individual meibocytes also seem to be more intensely stained, indicating the membrane-bound localization of DSG. ( B ) Transition of the disintegration zone (d) of an acinus (ac) into the connecting duct (cd). Parts of the duct are filled with degenerated cells and meibum and show a weak DSG reaction. The epithelium of the connecting duct is also positive for DSG, especially apically toward the lumen. Conjunctiva (cj). ( C ) Positive control is the detection of DSG in the epidermis (epi) of the eyelid. ( D ) The negative control shows no immunoreaction. The figure shows representative results of three independent experiments ( n = 3). DSG, desmoglein.

    Article Snippet: DSG , Acris Antibodies , SP1051 , IHC (1:200); IF (1:200); WB (1:250).

    Techniques: Immunohistochemical staining, Staining, Membrane, Positive Control, Negative Control